Nausea

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Nausea

Postby palmspringsbum » Thu Nov 09, 2006 1:56 pm

:kaffee2: This article isn't really about marijuana & nausea, as I find articles dealing specifically with that I will ad them. The great advantage smoking marijuana has for nausea is that you don't have to swallow anything and it works in minutes - something nothing else can claim. Ask any cancer patient that's tried it.

What I can't help wondering is when, if ever, a study will be done on the children of pregnant women who use cannabis for nausea. I speculate the results would be astonishing, and most positive.

The Naples News wrote:Jane Brody: It's unnecessary for women to suffer from nausea, vomiting in silence

Jane Brody - The New York Times

Tuesday, November 7, 2006

Anyone who has ever been nauseated knows what an awful feeling it is. Yet for millions of Americans, nausea and its frequent aftermath, vomiting, are facts of life that occur periodically over many months.

Although there are now safe and effective ways to prevent and to treat predictable cases, like those involving pregnant women and cancer patients, many people who could benefit fail to receive adequate treatment, if any treatment at all.

In the 1960s, a friend of mine spent her two pregnancies nauseated and vomiting. By the time her sons were born, she looked like a poorly nourished scarecrow. Fortunately, both babies, true to their role as parasites, were hale and hearty at birth.

Another friend soon to give birth to twins was so sick during her first trimester that she hardly left the house, and she lost weight instead of gaining it.

Infants of those severely afflicted through their pregnancies — the condition is known medically as hyperemesis gravidarum — typically have lower than normal birth weights for their gestational age. Up to 2 percent of pregnant women experience such severe and protracted vomiting that hospitalization is necessary to keep them from becoming dangerously dehydrated and to keep their weight up.

Nausea and vomiting affects 70 percent to 85 percent of pregnant women for varying lengths of time. Half of pregnant women have both nausea and vomiting, a quarter have nausea only, and the remaining quarter are spared.

For many women, nausea and vomiting is their first indication that they are pregnant. Typically, the distress dissipates after about 12 weeks, and women who experience it are often reassured by friends and relatives that it is an indication of a healthy pregnancy. Indeed, there is a lower rate of miscarriage among women with nausea and vomiting of any severity; even hyperemesis gravidarum most often results in a good outcome.

Alas, for large numbers of pregnant women, so-called morning sickness, although it can occur at any and all hours of the day, is often minimized by their physicians and thus undertreated, according to a report in 2004 from the American College of Obstetricians and Gynecologists.

In a clinical guidance bulletin for obstetrician-gynecologists, the college wrote that an investigator found that among women who called a help line for those with nausea and vomiting during pregnancy and who subsequently terminated pregnancy because of these afflictions, fewer than 50 percent were offered anti-emetic therapy.

"Of those offered treatment, 90 percent were offered regimens that were not likely to be effective," the bulletin says. "Furthermore, some women do not seek treatment because of concerns about safety."

It is true that most women today are terrified of taking any medication during pregnancy. Some may remember the voluntary withdrawal of the drug Bendectin by Merrell Dow after a barrage of lawsuits amid claims that it caused birth defects. At the time, Bendectin (doxylamine) was being used by about a quarter of pregnant women to relieve nausea and vomiting.

Since then, multiple studies have exonerated the drug and found it to be safe and effective. In the hierarchy of remedies for nausea and vomiting due to pregnancy, the practice bulletin ranks a combination of doxylamine and vitamin B6 among "first-line therapies." The drug combination can be legally prescribed and prepared by compounding pharmacies upon request.

Other drugs deemed safe and effective include phenothiazines and trimethobenzamide.

Before going the drug route, however, there are lifestyle and diet options that are effective for many women, according to the March of Dimes. Most important:<ul class=postlist><li>Eat frequent small meals, five or six a day. Hence the classic advice to keep crackers at the bedside and to consume several before getting up in the morning.</li>

<li>Get up slowly in the morning, sitting on the bed for a few minutes before standing up.</li>

<li>Eat snacks high in protein, like nuts and peanut butter.</li>

<li>Drink fluids often during the day, including broth, cola and a sports drink like Gatorade.</li>

<li>Get plenty of fresh air.</li>

<li>Avoid smells that you find unpleasant and foods that are hard to digest, like fatty foods.</li>

<li>Avoid drinking citrus juice, milk, coffee, and tea with meals.</li></ul>Capsules of powdered ginger have been found in a few studies to reduce episodes of nausea and vomiting in pregnant women.

Several of the most effective drugs used to treat cancer, as well as radiation therapy involving the digestive tract, cause nausea and vomiting for up to 75 percent of the people treated, and it is the side effect most feared by cancer patients.

If untreated, nausea and vomiting caused by cancer therapy can result in dehydration, fatigue, difficulty concentrating, slow healing of wounds, and loss of appetite, according to a bulletin produced by the American Cancer Society and National Comprehensive Cancer Network.

Many cancer patients insist that marijuana is the best remedy for this problem. But the United States Supreme Court has refused efforts to legalize marijuana as a medical treatment.

Even without marijuana, however, most patients do not have to suffer. There are now quite a few legal remedies that can treat and even prevent nausea and vomiting. Most often, the anti-nausea remedy is started before the chemotherapy is administered.

The treatments selected are determined by how likely the therapy is to cause nausea and vomiting. For example, for chemotherapy low on the nausea scale, Compazine may be used.

For therapies more likely to cause nausea and vomiting, two anti-nausea drugs may be used in combination. One such remedy recently approved by the Food and Drug Administration is Emend, by Merck. Taking one capsule a day for three days starting before chemotherapy can help prevent nausea and vomiting. Emend may be combined with another drug when chemotherapy, for example high-dosage cisplatin, is highly likely to cause nausea and vomiting.

Other helpful measures include acupuncture, biofeedback, and relaxation techniques.

<hr class=postrule>

<span class=postbold>What you can do </span>

Here are tips from the American Cancer Society regarding nausea related to treatment:<ul class=postlist><li>Eat frequent small meals</li>

<li>Eat at least an hour before your treatment</li>

<li>Avoid fried and fatty foods</li>

<li>Restrict fluids with meals</li>

<li>Eat foods cold or at room temperature</li>

<li>Have someone else prepare meals if you feel nauseated</li>

<li>Limit exposure to sounds, sights and smells that cause nausea</li>

<li>Avoid favorite foods when nauseated</li>

<li>Wear loose-fitting clothes</li>

<li>Freshen the air with a fan or open window.</li></ul>Free copies of the bulletin, Nausea and Vomiting Treatment Guidelines for Patients With Cancer, can be ordered through the Web sites www.nccn.org and www.cancer.org, or by calling 1-888-909-NCCN or 1-800-ACS-2345.

© 2006 Naples Daily News and NDN Productions. Published in Naples, Florida,

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Oral THC Eased Gastric Bypass Nausea

Postby palmspringsbum » Sat Feb 09, 2008 1:02 am

BBSNews wrote:
Oral THC Eased Gastric Bypass Nausea


BBSNews
Sunday, February 03 2008 @ 01:11 PM EST
Edited by: Michael Hess

<span class=postbigbold>Science: THC effective in intractable nausea in a patient undergoing gastric bypass surgery</span>

BBSNews 2008-02-03 -- (IACM) Californian doctors presented a case-report of a 31-year old woman with a long history of obesity, who underwent gastric bypass surgery to reduce her food intake. Within the following weeks she developed severe nausea and inability to tolerate fluids or food and was admitted to hospital seven times. A variety of anti-emetic drugs were tried including a serotonin antagonist, which only provided limited relief. Finally, the patient asked her gastric bypass be reversed. As a last resort, oral THC was prescribed with a maximum of 15 mg per day. She noticed a significant improvement in her symptoms within 1-2 days and tolerated the medication well. Her mood and energy levels improved quickly and she began tolerating more foods and liquids by mouth. She used THC for less than 4 weeks.

Gastric bypass surgery makes the stomach smaller and allows food to bypass part of the small intestine. The patients feel full more quickly, which reduces food intake. Bypassing part of the intestine also results in fewer calories being absorbed leading to weight loss. Nausea is a well-documented post-operative complication of this intervention, which often responds to standard treatments, but occasionally is unresponsive. The authors noted that "THC could have a useful role in treating this serious and debiliating post-operative complication."

(Source: Merriman AR, Oliak DA. Use of medical marijuana for treatment of severe intractable nausea after laparoscopic Roux- en-Y gastric bypass surgery: case report. Surg Obes Relat Dis 2008 Jan 26 [Electronic publication ahead of print])

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